Uterus transplantation (UTx) research has been introduced in several countries, with trials in Sweden and the United States producing successful outcomes. The growing interest in developing UTx trials in other countries, such as Spain, the Netherlands, Japan, and Australia, raises important questions regarding the ethics of surgical innovation research in the field of UTx. This paper examines the current state of UTx in the context of the surgical innovation paradigm and IDEAL framework and discusses the ethical challenges faced by those (...) considering the introduction of new trials. We argue that UTx remains an experimental procedure at a relatively early stage of the IDEAL framework, especially in the context of de novo trials, where protocols are likely to deviate from those used previously and where researchers are likely to have limited experience of UTx. We conclude that countries considering the introduction of UTx trials should build on the strengths of the reported outcomes to consolidate the evidence base and shed light on the uncertainties of the procedure. Authorities responsible for the ethical governance of UTx trials are advised to draw on the ethical framework used in the oversight of surgical innovation. (shrink)

In this paper we defend that elective ventilation (EV), even if conceived as the instrument to maximise the chances of organ recovery, is mainly the means to provide the patient who is dying with a dignified death in several ways, one of them being the possibility of becoming an organ donor. Because EV does not harm the patient and permits the medical team a better assessment of the patient's clinical trajectory and a better management of the dying process by the (...) family, EV does not violate the principle of non-beneficence nor the principle of autonomy if we restrict the initiation of EV to those cases in which it is not known what the previous wishes of the patient were as regards to his or her care at the end of life. (shrink)

Diseases of complex origin have a component of quantitative genetics that contributes to their susceptibility and phenotypic variability. However, after several studies, a major part of the genetic component of complex phenotypes has still not been found, a situation known as “missing heritability.” Although there have been many hypotheses put forward to explain the reasons for the missing heritability, its definitive causes remain unknown. Complex diseases are caused by multiple intermediate phenotypes involved in their pathogenesis and, very often, each one (...) of these intermediate phenotypes also has a component of quantitative inheritance. Here we propose that at least part of the missing heritability can be explained by the genetic component of intermediate phenotypes that is not detectable at the level of the main complex trait. At the same time, the identification of the genetic component of intermediate phenotypes provides an opportunity to identify part of the missing heritability of complex diseases. (shrink)

RESUMEN La neurociencia ha proporcionado valiosas herramientas para analizar problemas filosóficos; sin embargo, el debate sobre el papel de las evidencias neurocientíficas en la explicación de determinados fenómenos mentales sigue abierto. La discusión se centra en la experiencia mística y sus bases neuronales, lo que permite efectuar consideraciones más genéricas acerca de la legitimidad y el alcance de los razonamientos neurocientíficos cuando versan sobre algunos de los más conspicuos productos de la cultura. ABSTRACT Neuroscience has provided valuable tools for the (...) analysis of philosophical problems; however, there is an ongoing debate over the role of neuroscientific evidence in the explanation of certain mental phenomena. The discussion focuses on the mystical experience and its neuronal bases, which makes it possible to carry out more generic considerations regarding the legitimacy and scope of neuroscientific arguments when they involve some of the principal cultural products. (shrink)

The presence of patients’ families during cardiopulmonary resuscitation (CPR) is a controversial topic, due to its repercussions for clinical practice. While family members’ presence may help them to overcome their grief, it could be detrimental, as it may case posttraumatic stress disorder (PTSD), and there is the possibility that family members may interfere with the procedure. For these reasons, families’ presence during CPR has rejected by some healthcare providers.To research concerns about families’ presence among providers dealing with CPR in the (...) Fundación Hospital Alcorcón (Madrid), I performed this study. Of the 190 providers surveyed, 115 submitted a complete questionnaire. The most frequently reported concerns were interference (78.3 percent of respondents), and PTSD (69.6 percent of respondents). Fewer pediatric providers were concerned about PTSD than other providers (41.2% percent versus 74.5 percent, p = 0.01). Providers were reluctant to offer families the option of being present unless they had requested it, and would only permit it under certain conditions. Having a staff member to support the family was of great value to most respondents. The author believes families have a negative right to be present during CPR and so should be invited to stay. (shrink)

The aim of this paper is to analyze the idea of general resurrection of the dead at the end of times in the synoptic Gospels. We intend to clarify whether this concept can be interpreted as a transposition of the parallel belief contained in some intertestamental writings, or if the singularity of the religious experience expressed in the synoptic Gospels establishes an inexorable moment of discontinuity with the previous apocalyptic framework, making it impossible to understand this doctrine on the sole (...) basis of its Jewish precedents. In order to accomplish our goal, we shall first study the general resurrection of the dead in the Q source, the references to this notion in the gospel of Mark, and its meaning in both Matthew and Luke. We will exclude from our treatment all the topics related with the resurrection of Jesus, and we will be focused on the explicit mentions of the doctrine of the resurrection of the dead as such. Since implicit beliefs are always difficult to assess, especially in the context of eschatological ideas, in which vagueness and absence of a systematic effort of exposition often prevail, we will not allude to other synoptic passages which have been regarded as potential expressions of the doctrine of the resurrection of the dead at the end of times. (shrink)

Health professionals are especially exposed to stress, with consequences on professionals’ health and wellbeing. However, palliative care professionals’ wellbeing has been the subject of very little research. The aim of this work is to study the Personal Wellbeing Index in a sample of Spanish palliative care professionals, as well as to study their levels of wellbeing and the relationships of wellbeing with variables such as gender, age, marital status, profession, and professional quality of life. A cross-sectional survey of Spanish palliative (...) care professionals was conducted. The Spanish version of the PWI and the Short version of the Professional Quality of Life Scale were used. Here, 296 palliative care professionals attending patients at the end of life participated in the study. They showed medium to high levels of wellbeing. The PWI showed an adequate internal structure [χ2 = 116.130 ]; Comparative Fit Index = 0.970; standardized root mean square residual = 0.041; root mean square error of approximation = 0.140 ] and excellent estimates of reliability [α = 0.879 and Composite Reliability Index = 0.923]. Wellbeing was higher for married compared to single and showed no relation with age, gender, and profession. Additionally, a structural equation model was estimated, in which a positive relation was found between wellbeing and compassion satisfaction and a negative one with burnout. The PWI is adequate to measure personal wellbeing in Spanish palliative care professionals. (shrink)

The present study aims to explore whether the symptoms associated with fibromyalgia are contextually influenced by the area of residence. Furthermore, it is analyzed whether the effect of the acceptance of the disease on the emotional, cognitive and physical symptoms is moderated by the patients’ place of residence. Using a cross-sectional design, a total of 234 women with fibromyalgia were surveyed, of which 55.13% resided in rural areas and 44.87% in urban areas. Self-reported questionnaires were used to assess pain severity, (...) anxiety and depression, functional limitation, physical and mental fatigue and acceptance of the disease. The results show significant differences in acceptance, pain, and physical and mental fatigue between patients from rural and urban areas. The rural area patients presented higher levels of acceptance and pain and lesser levels of physical and mental fatigue compared to the urban area. The moderation analysis add that, only in patients from the rural area, the variables of physical symptoms were significantly and negatively associated with acceptance. This study addresses for the first time the role of the place of residence in suffering from fibromyalgia, suggesting that the rural or urban environment plays a relevant role in the severity and/or management of symptoms in fibromyalgia women. Limitations and practical implications are also discussed. (shrink)

El artista chileno José Miguel Blanco tuvo un rol protagónico en la escena cultural del país durante la segunda mitad del siglo XIX. Aparte de su labor escultórica, traducida en una cantidad importante de obras, una buena parte de su quehacer estuvo vinculado con la escritura de arte, lo que se materializó, principalmente, en el periódico El Taller Ilustrado, el primer medio informativo en el país dedicado exclusivamente a temas de arte, que este escultor creó y dirigió por casi (...) cinco años. Desde esa tribuna Blanco promovió información, debates e iniciativas que favorecieron el desarrollo cultural del país. Este escultor es, sin lugar a dudas, el autor más prolífico en la escritura artística chilena de su tiempo. The Chilean artist José Miguel Blanco had a protagonic role in the culture scene in the country during the second half of the 19th century. Besides his works of sculpture, reflected in an important quantity of pieces of art, a great part of his work was related to the Artistic Writing, which was materialized, mainly in the newspapers called El Taller Ilustrado, the first informative media in the country dedicated exclusively to the topics of Art, that this sculptor created and managed for almost five years. From this tribune, Blanco promoted information, debates and initiatives that contributed to the development of culture in Chile. The sculptor is, without any doubt, the most prolific author in Chilean Artistic Writing in his time. (shrink)

Este texto se sitúa en la juntura de los feminismos del sur que señalaron el encubrimiento de la heterogeneidad de las mujeres indo-afro-latino-americanas. Desde las cadencias y los ritmos de las voces de mujeres de Nuestra América cuyos saberes interrumpen, disrumpen e intervienen muestra que los problemas del feminismo blanco burgués del norte no son los de todas las mujeres puesto que algunas mujeres escapan a la fragilidad femenina que justifica el paternalismo y los micromachismos dentro y fuera de (...) la academia, incluso dentro y fuera de la misma clase, etnia o generación. Desde los feminismos del sur se propone habilitar un diálogo entre/con “las otras” de nosotras no sólo para articular teóricamente y coalicionar políticamente nudos epistémicos que pongan en crisis el modelo de la representación y con ello una revisión del punto de vista, sino también para desmontar, paralelamente desde la ontología relacional que suponen, el privilegio epistemológico, la violencia epistémica y el extractivisimo académico que ubica y posiciona a unas sobre otras en la reproducción de “las otras de nosotras”. A partir de los posicionamientos de María Lugones, Rita Segato, Aura Cumes, Lorena Cabnal y Julieta Paredes, se propone visibilizar los nudos epistemológicos venidos de los feminismos comunitarios e indígenas que habilitan ampliaciones metodológicas desde las que podrían configurarse una historia de las resistencias de las mujeres de Latinoamérica en la exterioridad de los paradigmas euronortecentrados. (shrink)

El siguiente texto incluye la nota del autor y dedicatoria del poema épico de G. K. Chesterton, La Balada del Caballo Blanco (1911) y la nota del traductor del poema. Estos textos están reproducidos de la traducción de este poema de J. Marcos Pérez Rabasa publicada en Buenos Aires, Argentina y presentada en el el Centro Cultural Borges, de esa ciudad, durante la conferencia del Instituto Chesterton, “Cien años de la Balada del Caballo Blanco” Esta es la (...) primera traducción a la lengua Española. Chesterton dedicó este poema a su esposa Frances. (shrink)

A systematic effort to rethink Freud's theory of the unconscious, aiming to separate out the different forms of unconsciousness.

The current study analyzed the relationship between Coronavirus Awareness, mental health, and willingness to seek professional psychological help. This was made through a quantitative approach, using online questionnaires to collect data from 855 subjects. The questionnaires included the Brief Symptom Inventory to measure mental health indicators, the Attitudes Toward Seeking Professional Psychological Help Scale–Short Form, and the Coronavirus Awareness Scale-10. An Exploratory Factor Analysis suggests that three factors underlie the CAS-10: Coronavirus Concern, Exaggerated Perception, and Immunity Perception. Results indicate a (...) significant positive correlation between Coronavirus Concern and both general anxiety and phobic anxiety symptoms. Immunity Perception is positively related to paranoid ideation and psychotic symptoms. A Mediation Analysis determined that Coronavirus Concern has a significant positive direct effect on Openness to Seeking Psychological Treatment, while Exaggerated Perception and Immunity Perception scores have significant direct negative effects on the Value and Need in Seeking Treatment scores. Indirectly, the relationship between Coronavirus Concern and OPST is significantly mediated by anxiety symptoms. Similar results were found for the VNST subscale. There is a negative significant effect of Immunity Perception over OSPT mediated by Paranoid Ideation. However, the overall model only achieved small r2 coefficients for the OSPT and VNST scores. Comparisons in Coronavirus Awareness between sex, age, and the presence of children and older adults at home were also made. These results are discussed regarding their practical implications for mental health providers and policymakers. (shrink)

In this paper I propose to conceive of forgiveness as a process of eliminating punitive reactive attitudes, which makes up part of the offended person’s willingness to reestablish a certain type of reciprocal relationship with the offender. Distinguishing among types of reciprocity allows us to realize that forgiveness is a more varied phenomenon than is usually assumed in the philosophical literature, as well as to understand why the dispute concerning the gratuitousnessconditionality of forgiveness is meaningless.

En 2014 la Corte Constitucional solicito a varias universidades “un concepto científico acerca de los efectos que para el desarrollo integral del menor podría tener el hecho de ser adoptado por personas de un mismo sexo”. Este concepto fue requerido en virtud de la demanda 10135/14 por parte del ciudadano Diego Andrés Prada Vargas contra los artículos 64, 66 y 68 y contra el artículo primero de la Ley 54 de 1990, los cuales excluyen a parejas del mismo sexo para (...) la adopción. Por solicitud del director del Departamento de Psicología, elabore un concepto ratificando lo planteado en Domínguez, al mostrar que los estudios internacionales desde el repertorio empirico-analitico han comprobado que el cuidado y la proveeduría dependen cada vez menos del género y la orientación sexual. La corte constitucional nuevamente desconoció los conceptos científicos favorables a las familias homoparentales, y solamente ratifico la adopción en el caso de que uno de los integrantes de la pareja fuera la madre biológica o el padre biológico. Al continuar la controversia, propongo revisar las reclamaciones de justica de la demanda 10135/14 desde las propuestas de un “pacto de cuidado” y de “neutralidad con respecto de Appiah en cuanto a: el reconocimiento a las personas del mismo sexo de su “deseo de vivir bien”, la obligatoriedad de reglamentar la adopción para personas del mismo sexo o la custodia para padres biológicos en esta situación ; y la inclusión dentro del pacto de cuidado de hijas o hijos de familias homoparentales en la educación al valorar la donación por parte de las parejas homosexuales de una socialización primaria basada en la estima y el respeto. Primero, presento las avances de la jurisprudencia colombiana frente a los derechos de los homosexuales, muestro como la solicitud de conceptos psicológicos sobre las personas homosexuales ha sido una estrategia dilatoria, y propongo revisar las pretensiones de la demanda 10135/14 en cuanto a las razones suficientes para encontrar una distancia justa hacia el derecho a un pacto de cuidado para la _debida inclusión_ de familias monoparentales en los beneficios y obligaciones frente al estado. (shrink)

Esta investigación busca comprender el sustrato emocional en los planes de vida de los jóvenes universitarios, en cuanto a sus juicios de valor sobre una vida digna y buena en situaciones de vulnerabilidad, así como la intencionalidad y los modos de comunicación de estos en la experiencia universitaria. A partir de la propuesta investigativa hermenéutica narrativa de Quintero-Mejía, se interpretaron las emociones morales presentes en las tramas de planes de vida de los estudiantes de la Universidad Nacional de Colombia. El (...) autoexamen reveló los conflictos emocionales sobre las situaciones vulnerables que escaparon al control, y los juicios reconstructivos mostraron cómo el miedo, la culpa, la vergüenza o la humillación afectaron el equilibrio emocional. Además, cada estudiante mostró, los juicios compromisorios para el bien propio y creencias hacia el bien común. (shrink)

RESUMENEn este artículo se ponen de manifiesto algunos aspectos de la ética pontiana. El núcleo gira en torno al sujeto como ente relacional. Este aparece inmerso en una praxis intersubjetiva que impregna el obrar humano en conexion incesante con el mundo, físico, cultural y socialPALABRAS CLAVEMERLEAU-PONTY-ETICA-FENOMENOLOGIAABSTRACTThe paper focuses on Merleau-Ponty's ethics. it deals with the subject as a relational being. According to Merleau Ponty, the subject appears immersed within the intersubjective praxis of human action in the world, physical, cultural and (...) socia.KEYWORDSMERLEAU-PONTY-ETHICS-PHENOMENOLOGY. (shrink)

Se presenta en este trabajo la encrucijada actual de la interpretación de la novela más célebre de Gabriel García Márquez dando cuenta, por un lado, de una tradición interpretativa que desde una cierta idea de “lo nacional” relaciona el sentido de la obra con un agotamiento de la historia y, por otro lado, postulando las condiciones de posibilidad de otra interpretación, vale decir, otra tradición interpretativa desde donde leer la novela para hallar en ella otro sentido con relación a la (...) historia. La argumentación se apoya en postulados de la hermenéutica de Hans-Georg Gadamer y de Paul Ricoeur. (shrink)

Este trabajo tematiza el contraste entre la Novela Histórica Tradicional y la Nueva Novela Histórica en el contexto colombiano de la segunda mitad del siglo XX en cuanto a la representación del pasado nacional y, en particular, en cuanto al lugar del Otro en el tiempo/espacio de ese pasado. Se postula que los escritores colombianos de la Nueva Novela Histórica, al tematizar la presencia del Otro culturalmente diferente al sujeto de la élite republicana, son un antecedente cultural de la Constitución (...) política del 91, que reconoce la calidad pluricultural de la nación colombiana. This paper analyses the contrast between the Traditional Historical Novel and the New Historical Novel in the Colombian context of the second half of the XX century with reference to the representation of the national past and specifically referring to the estimation of the other as far as time and space in the past is concerned. i will argue that Colombian writers of the New Historical Novel mark the presence of the Other, who is culturally different from the republican elite, the main subject, and thus these works become the cultural background of the Political Constitution of 1991, that recognizes the multicultural situation of the Colombian nation. (shrink)

This article examines the role of social media and journalistic media in presidential electoral processes. A systematic review of scientific articles published from 2012 to 2022 was conducted. The results indicate that the media has a significant influence on public perception and the political agenda during election campaigns. Furthermore, the importance of evaluating political leaders in the voters' decision-making process is emphasized. In summary, the article provides valuable insights into how the media can shape the narrative and public opinion during (...) presidential elections. (shrink)

El jesuita morisco P. Ignacio de las Casas colaboró en la traducción de algunos de los libros plúmbeos encontrados en Granada a fines del siglo XVI. Inicialmente se manifestó partidario de su autenticidad, pero pronto se convenció de que eran una falsificación. Desarrolló entonces una activa lucha para conseguir que la Iglesia evitara su divulgación. En el artículo se pasa revista a su intervención como traductor y a los argumentos que utilizó para criticar la doctrina de los libros plúmbeos. El (...) P. Las Casas, además de señalar la presencia de elementos islámicos, ve en ellos claras muestras de antiguas herejías antitrinitarias. Aunque no los considera obra de moriscos, señala el atractivo que el mesianismo y milenarismo contenidos en la doctrina de los libros plúmbeos tenía para los moriscos. (shrink)

Positive reappraisal strategies have been found to reduce negative affect following the recall of negative personal events. This study examined the restorative effect of two mood-repair instructions (self-compassion vs benefit-focused reappraisal) and a control condition with no instructions following a negative Mood Induction Procedure by using the guided recall of a negative autobiographical event. A total of 112 university students participated in the online study (81% women, Mage: 21.0 years). Immediately following the negative memory recall, participants were randomised to each (...) condition [(self-compassion: n = 36, benefit-focused: n = 39) or a control condition (n = 37)]. Repeated measures ANOVAs 3 (Repair condition) × 3 (Time of mood assessment: pre-recall, post-recall, post-regulation) showed that, as expected, negative mood (sadness, shame, and guilt) worsened significantly after the guided recall in all groups (p <.001). After the mood-repair intervention, participants in the self-compassion and benefit-focused conditions showed a significant reduction in negative mood (p <.019), while such improvement was not observed in the control group. Self-compassion and benefit-focused reappraisal functioned similarly as mood repair strategies after experiencing negative affect induced by the recall of negative personal memories. Implications in the context of autobiographical memory biases are discussed. (shrink)

This paper defends the claim that pragmatic encroachment—the idea that knowledge is sensitive to the practical stakes of believing—can explain a distinctive kind of epistemic injustice: the injustice that occurs when prejudice causes someone to know less than they otherwise would. This encroachment injustice, as we call it, occurs when the threat of being met with prejudice raises the stakes for someone to rely on her belief when acting, by raising the level of evidential support required for knowledge. We explain (...) this notion of encroachment injustice, connect it to the empirical literature on implicit bias, and defend it against important objections. (shrink)